NPTN Protein (His tag)

Produktnummer ABIN7318820

Recombinant NPTN-Protein exprimiert in Human Cells.

Kurzübersicht für NPTN Protein (His tag) (ABIN7318820)

Target: NPTN (Neuroplastin (NPTN))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses NPTN Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Neuroplastin/NPTN Protein (His Tag)

Sequenz: Gln29-His220

Produktmerkmale: Recombinant Human Neuroplastin is produced by our Mammalian expression system and the target gene encoding Gln29-His220 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: NPTN (Neuroplastin (NPTN))

Andere Bezeichnung: Neuroplastin/NPTN

Hintergrund:

Background: Neuroplastin (NPTN) is a 52-57 kDa member of the Ig-superfamily. Neuroplastin likely serves as a cell adhesion molecule, and is widely expressed in multiple tissues. Human Neuroplastin is 282 amino acids that contions two Ig-like domains and a 38 aa cytoplasmic region. Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. Neuroplastin may also regulate neurite outgrowth by activating the FGFR1 signaling pathway. It may play a role in synaptic plasticity.

Synonym: Neuroplastin, Stromal Cell-Derived Receptor 1, SDR-1, NPTN, SDFR1, SDR1

Molekulargewicht: 22.7 kDa

UniProt: Q9Y639

Pathways: Regulation of long-term Neuronal Synaptic Plasticity