SGSH Protein (His tag)

Produktnummer ABIN7318838

Recombinant SGSH-Protein exprimiert in Human Cells.

Kurzübersicht für SGSH Protein (His tag) (ABIN7318838)

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses SGSH Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human SGSH Protein (His Tag)

Sequenz: Arg21-Leu502

Produktmerkmale: Recombinant Human N-Sulphoglucosamine Sulphohydrolase is produced by our Mammalian expression system and the target gene encoding Arg21-Leu502 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2,10 % Glycerol, pH 7.5.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Andere Bezeichnung: SGSH

Hintergrund:

Background: N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.

Synonym: N-Sulphoglucosamine Sulphohydrolase, Sulfoglucosamine Sulfamidase, Sulphamidase, SGSH, HSS

Molekulargewicht: 55.7 kDa

UniProt: P51688

Pathways: Glycosaminoglycan Metabolic Process