LUM Protein (His tag)

Produktnummer ABIN7320810

Dieses Recombinant LUM-Protein wird in Human Cells exprimiert.

Kurzübersicht für LUM Protein (His tag) (ABIN7320810)

Target: LUM (Lumican (LUM))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses LUM Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse Lumican/LUM Protein (His Tag)

Sequenz: Gln19-Asn338

Produktmerkmale: Recombinant Mouse Lumican is produced by our Mammalian expression system and the target gene encoding Gln19-Asn338 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: LUM (Lumican (LUM))

Andere Bezeichnung: Lumican/LUM

Hintergrund:

Background: Keratan sulfate proteoglycan lumican, mostly known as lumican, belongs to the SLRP class II subfamily and the small leucine-rich proteoglycan (SLRP) family. Lumican binds to laminin. It has positive regulation of transcription from RNA polymerase II promoter and transforming growth factor beta1 production. Lumican is expressed in a variety of tissues, including skin, artery, lung, cornea, kidney, bone, aorta, and articular cartilage. The abnormal connective tissue phenotype seen in the Lumican null mice shows the importance of the role of Lumican in collagen fibrillogenesis. In addition to the control of collagen fibril assembly, Lumican has been shown to play a role in the regulation of cell proliferation, migration, and adhesion.

Synonym: Keratan sulfate proteoglycan lumican,KSPG lumican,Lumican, LDC

Molekulargewicht: 37.4 kDa

UniProt: P51885

Pathways: Glycosaminoglycan Metabolic Process