KIF1BP Protein (His-GST)

Produktnummer ABIN7317164

Dieses Recombinant KIF1BP-Protein wird in Baculovirus infected Insect Cells exprimiert.

Kurzübersicht für KIF1BP Protein (His-GST) (ABIN7317164)

Target: KIF1BP (KIAA1279) (KIAA1279)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses KIF1BP Protein ist gelabelt mit His-GST.

Verwendungszweck: Recombinant Human KIAA1279 Protein (His & GST Tag)

Sequenz: Met 1-Thr621

Produktmerkmale: A DNA sequence encoding the human KIAA1279 (Q96EK5) (Met1-Thr621) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: KIF1BP (KIAA1279) (KIAA1279)

Andere Bezeichnung: KIAA1279

Hintergrund: KBP,KIAA1279,TTC20,KIFBP (Kinesin Family Binding Protein, also known as KIAA1279 and KIF1BP) is a Protein Coding gene. This gene encodes a kinesin family member 1 binding protein that is characterized by two tetratricopeptide repeats. The encoded protein localizes to the mitochondria and may be involved in regulating the transport of the mitochondria. Homozygous nonsense mutations in KIAA1279 at 1q22.1, encoding a protein with two tetratricopeptide repeats, underlie this syndromic form of Hirschsprung disease and generalized polymicrogyria, establishing the importance of KIAA1279 in both enteric and central nervous system development. KIAA1279 is widely expressed in the brain, testis, and other tissues. Diseases associated with KIFBP include Goldberg-Shprintzen Syndrome and Shprintzen-Goldberg Craniosynostosis Syndrome.

Molekulargewicht:

Calculated MW: 99.6 kDa

Observed MW: 92-102 kDa

Gen-ID: 26128

UniProt: Q96EK5