IL17F Protein (AA 31-163) (His tag)
Kurzübersicht für IL17F Protein (AA 31-163) (His tag) (ABIN7318651)
Target
Alle IL17F Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 31-163
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Aufreinigungstag / Konjugat
- Dieses IL17F Protein ist gelabelt mit His tag.
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Verwendungszweck
- Recombinant Human Interleukin-17F/IL-17F Protein
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Sequenz
- Arg31-Gln163
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Produktmerkmale
- Recombinant Human Interleukin-17F is produced by our E.coli expression system and the target gene encoding Arg31-Gln163 is expressed.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- < 0.1 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Measure by its ability to induce IL-6 secretion in 3T3 cells. The ED50 for this effect is <20 ng/mL.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile 20 mM sodium acetate, pH 4.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Haltbarkeit
- 12 months
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- IL17F (Interleukin 17F (IL17F))
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Andere Bezeichnung
- Interleukin-17F/IL-17F
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Hintergrund
- Cytokine ML,Interleukin,CANDF,IL17F,CANDF6,IL-17F,ML-1,ML1,Cytokine ML-1,IL24,IL-24,Interleukin-17F,Interleukin-24,Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.
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Molekulargewicht
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Calculated MW: 15.8 kDa
Observed MW: 18 kDa
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Gen-ID
- 112744
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UniProt
- Q96PD4
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
Target
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