IP6K1 Protein (His-GST)
Kurzübersicht für IP6K1 Protein (His-GST) (ABIN7196191)
Target
Alle IP6K1 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses IP6K1 Protein ist gelabelt mit His-GST.
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Verwendungszweck
- Recombinant Human IHPK1 Protein (His & GST Tag)
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Sequenz
- Met 1-Gln 441
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Produktmerkmale
- A DNA sequence encoding the human IHPK1 (Q92551-1) (Met1-Gln441) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Inositol Hexakisphosphate Kinase 1 (IP6K1) (AA 182-275) protein (GST tag)
IP6K1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Inositol Hexakisphosphate Kinase 1 (IP6K1) (AA 1-441) protein (His tag)IP6K1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Haltbarkeit
- 6 months
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- IP6K1 (Inositol Hexakisphosphate Kinase 1 (IP6K1))
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Andere Bezeichnung
- IHPK1
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Hintergrund
- IHPK1,PiUS,IHPK1 is a inositol hexaphosphate kinase (IHPK) protein which belongs to the inositol phosphokinase (IPK) family. IHPK proteins are likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). IHPK1 may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. During cell death, IHPK1 activity is enhanced, and intracellular InsP7 level is augmented. The distribution of IHPK1 or another predisposing gene affected by position effect of translocation may explain the T2DM phenotype at least in this family.
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Molekulargewicht
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Calculated MW: 78.0 kDa
Observed MW: 88 kDa
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Gen-ID
- 9807
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UniProt
- Q92551
Target
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