HYAL1 Protein (His tag)

Produktnummer ABIN7318588

Dieses Recombinant HYAL1-Protein wird in Human Cells exprimiert.

Kurzübersicht für HYAL1 Protein (His tag) (ABIN7318588)

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses HYAL1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Hyaluronidase-1/HYAL1 Protein (His Tag)

Sequenz: Phe22-Trp435

Produktmerkmale: Recombinant Human Hyaluronidase-1 is produced by our Mammalian expression system and the target gene encoding Phe22-Trp435 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 7.5.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Andere Bezeichnung: Hyaluronidase-1/HYAL1

Hintergrund:

Background: Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly expressed in the lung, placenta, and skeletal muscle. HYAL1 is thought to be involved in cell proliferation, migration, and differentiation. It may play a role in promoting tumor progression and blocking the TGFB1-enhanced cell growth. Mutations in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.

Synonym: Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung Carcinoma Protein 1, LuCa-1, HYAL1, LUCA1

Molekulargewicht: 47.2 kDa

UniProt: Q12794

Pathways: Glycosaminoglycan Metabolic Process