HNMT Protein (GST tag)

Produktnummer ABIN7196099

Recombinant HNMT-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für HNMT Protein (GST tag) (ABIN7196099)

Target: HNMT (Histamine N-Methyltransferase (HNMT))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 85 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses HNMT Protein ist gelabelt mit GST tag.

Verwendungszweck: Recombinant Human HNMT Protein (GST Tag)

Sequenz: Met 1-Ala 292

Produktmerkmale: A DNA sequence encoding the human HNMT (AAH20677.1) (Met 1-Ala 292) was fused with the GST tag at the N-terminus.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 0.15M NaCl, pH 7.5

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: HNMT (Histamine N-Methyltransferase (HNMT))

Andere Bezeichnung: HNMT

Hintergrund:

Background: Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. follistatin are expressed and subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal, bone marrow, and placenta but perhaps most notably in anterior pituitary-the classical target tissue for inhibin, the activin-follistatin system may play a key role in early embryogenesis. Follistatin binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone follistatin is a binding protein to activin. Since activin binds to follistatin, it is imperative to determine the nature of the activin/follistatin binding complex.

Synonym: HMT,HNMT-S1,HNMT-S2

Molekulargewicht: 60.5 kDa