Granzyme D Protein (GZMD) (His tag)

Produktnummer ABIN7320541

Produktdetails

Target: Granzyme D (GZMD)

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Granzyme D Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse Granzyme D/GZMD Protein (His Tag)

Sequenz: Ile21-Leu252

Produktmerkmale: Recombinant Mouse Granzyme D is produced by our Mammalian expression system and the target gene encoding Ile21-Leu252 is expressed with a 6His tag at the C-terminus.

Reinheit: > 90 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Granzyme D (GZMD)

Andere Bezeichnung: Granzyme D/GZMD (GZMD Produkte)

Synonyme: CCP5 Protein, Ctla-5 Protein, Ctla5 Protein, granzyme D Protein, Gzmd Protein

Hintergrund:

Background: Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, but the function of granzyme D is unknown. Previous studies reported that granzyme D is developmentally regulated during pregnancy together with granzymes E, F, and G in granulated metrial gland cells and is upregulated by IL-2 and IL-15. Granzyme D was also suggested to have a role in stromal cell-lymphocyte interactions.

Synonym: Granzyme D, Gzmd

Molekulargewicht: 26.8 kDa

UniProt: P11033