Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (His tag)

Produktnummer ABIN7318537

Recombinant Glucose-6-Phosphate Dehydrogenase-Protein exprimiert in Human Cells.

Kurzübersicht für Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (His tag) (ABIN7318537)

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Glucose-6-Phosphate Dehydrogenase Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human G6PD Protein (His Tag)

Sequenz: Ala2-Leu515

Produktmerkmale: Recombinant Human Glucose-6-Phosphate 1-Dehydrogenase is produced by our Mammalian expression system and the target gene encoding Ala2-Leu515 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Andere Bezeichnung: G6PD

Hintergrund:

Background: Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. It is notable in humans that G6PD is remarkable for its genetic diversity. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.

Synonym: Glucose-6-Phosphate 1-Dehydrogenase, G6PD

Molekulargewicht: 60.2 kDa

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones