GMFB Protein
Kurzübersicht für GMFB Protein (ABIN7317274)
Target
Protein-Typ
Spezies
Quelle
Reinheit
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Verwendungszweck
- Recombinant Human GMFB Protein
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Sequenz
- Met 1-His142
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Produktmerkmale
- A DNA sequence encoding the human GMFB (Met1-His142) was expressed.
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Sterilität
- 0.2 μm filtered
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Biological Activity Comment
- Not validated for activity
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Haltbarkeit
- 12 months
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- GMFB (Glia Maturation Factor, beta (GMFB))
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Andere Bezeichnung
- GMFB
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Hintergrund
- GMF,GMF-beta,Glia maturation factor beta,GMFB is a nerve growth factor which belongs to the actin-binding proteins ADF family, GMF subfamily. GMFB is involved in nervous system development, angiogenesis and immune function. It is especially crucial for the nervous system. GMFB causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. It contains 1 ADF-H domain and is phosphorylated after phorbol ester stimulation. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.
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Molekulargewicht
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Calculated MW: 16.7 kDa
Observed MW: 17 kDa
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Gen-ID
- 2764
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NCBI Accession
- NP_004115
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UniProt
- P60983
Target
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