GABA Protein (GST tag)

Produktnummer ABIN7318511

Dieses Recombinant GABA-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für GABA Protein (GST tag) (ABIN7318511)

Target: GABA (gamma-Aminobutyric Acid (GABA))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses GABA Protein ist gelabelt mit GST tag.

Verwendungszweck: Recombinant Human GABA Protein (GST Tag)

Sequenz: Met 1-Lys117

Produktmerkmale: Recombinant Human GABA(A) Receptor-Associated Protein is produced by our E.coli expression system and the target gene encoding Met1-Lys117 is expressed with a GST tag at the N-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 200 mM NaCl, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: GABA (gamma-Aminobutyric Acid (GABA))

Andere Bezeichnung: GABA

Substanzklasse: Amino Acid

Hintergrund: GABA(A) Receptor-Associated Protein,GABARAP,GABARAP Protein,HCG1987397 Isoform CRA_b,Gamma-Aminobutyric Acid Receptor-Associated Protein (GABARAP) is a ligand-gated chloride channel protein that mediates inhibitory neurotransmission and belongs to the MAP1 LC3 family. GABARAP is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. GABARAP clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. An important inhibitory neurotransmitter, GABA, acts on GABA receptors that are ubiquitously expressed in the CNS. GABARAP has been shown to play a important role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton.

Molekulargewicht:

Calculated MW: 40.2 kDa

Observed MW: 37 kDa

UniProt: Q6IAW1