FH Protein (AA 45-510)

Produktnummer ABIN7318507

Dieses Recombinant FH-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für FH Protein (AA 45-510) (ABIN7318507)

Target: FH (Fumarate Hydratase (FH))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 45-510

Verwendungszweck: Recombinant Human Fumarase/FH Protein

Sequenz: Ala45-Lys510

Produktmerkmale: Recombinant Human Fumarase is produced by our E.coli expression system and the target gene encoding Ala45-Lys510 is expressed.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, pH 8.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: FH (Fumarate Hydratase (FH))

Andere Bezeichnung: Fumarase/FH

Hintergrund: FH,FMRD,Fumarase,Fumarate Hydratase Mitochondrial,HLRCC,LRCC,MCL,MCUL1,Fumarase is an enzyme that catalyze the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarase exists in both form, cytosolic formand N-terminal extend mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase is thought to act as a tumor suppressor, which deficiency can lead to progressive encephalopathy, cerebral atrophy and development delay.

Molekulargewicht:

Calculated MW: 50.2 kDa

Observed MW: 45 kDa

Gen-ID: 2271

UniProt: P07954