Fibrillin 1 Protein (FBN1) (His tag)

Produktnummer ABIN7319692

Dieses Recombinant Fibrillin 1-Protein wird in Human Cells produziert.

Kurzübersicht für Fibrillin 1 Protein (FBN1) (His tag) (ABIN7319692)

Target: Fibrillin 1 (FBN1)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Fibrillin 1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Fibrillin-1/FBN1 Protein (His Tag)

Sequenz: Ser2732-His287

Produktmerkmale: Recombinant Human Fibrillin-1 is produced by our Mammalian expression system and the target gene encoding Ser2732-His2871 is expressed with a 8His tag at the N-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Fibrillin 1 (FBN1)

Andere Bezeichnung: Fibrillin-1/FBN1

Hintergrund:

Background: Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream. In the liver asprosin activates rapid glucose release by a cAMP-dependent pathway. The glucose release by the liver into the blood stream is vital for brain function and survival during fasting. People with neonatal progeroid syndrome lack asprosin, while people with insulin resistance have it in abundance. In animal tests asprosin showed potential for treating type 2 diabetes. When antibodies targeting asprosin were injected into diabetic mice, blood glucose and insulin levels improved.

Synonym: Fibrillin-1, FBN1, Asprosin, FBN

Molekulargewicht: 17 kDa

UniProt: P35555

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interaktom