FABP5 Protein

Produktnummer ABIN7317355

Produktdetails

Target: FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Verwendungszweck: Recombinant Human FABP5 Protein

Sequenz: Met 1-Glu 135

Produktmerkmale: A DNA sequence encoding the human FABP5 (Q01469) (Met 1-Glu 135) was expressed and purified.

Reinheit: > 92 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, pH 8.0

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

Andere Bezeichnung: FABP5 (FABP5 Produkte)

Synonyme: E-FABP Protein, EFABP Protein, KFABP Protein, PA-FABP Protein, PAFABP Protein, FABP5 Protein, Fabpe Protein, Klbp Protein, mal1 Protein, C-FABP Protein, DA11 Protein, FABP5L1 Protein, fatty acid binding protein 5 Protein, fatty acid binding protein 5, epidermal Protein, fatty acid binding protein 5 (psoriasis-associated) Protein, fatty acid binding protein 5 pseudogene 1 Protein, cationic amino acid transporter 3 pseudogene Protein, FABP5 Protein, Fabp5 Protein, FABP5P1 Protein, LOC609554 Protein

Hintergrund:

Background: Fatty acid-binding protein; also known as Epidermal-type fatty acid-binding protein; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; E-FABP and FABP5; is a cytoplasm protein which Belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs ) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP / FABP5 is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. E-FABP / FABP5 exhibits an important role in binding free fatty acids; as well as regulating lipid metabolism and transport. E-FABP / FABP5 has high specificity for fatty acids. It has highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity of FABP5. E-FABP / FABP5 may be involved in keratinocyte differentiation.

Synonym: Fatty Acid-Binding Protein Epidermal; Epidermal-Type Fatty Acid-Binding Protein; E-FABP; Fatty Acid-Binding Protein 5; Psoriasis-Associated Fatty Acid-Binding Protein Homolog; PA-FABP; FABP5

Molekulargewicht: 15.2 kDa

UniProt: Q01469