Ethanolaminephosphotransferase 1 (SELENOI) protein (GST tag)

Produktnummer ABIN7318453

Recombinant Ethanolaminephosphotransferase 1-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für Ethanolaminephosphotransferase 1 (SELENOI) protein (GST tag) (ABIN7318453)

Target: Ethanolaminephosphotransferase 1 (SELENOI)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: GST tag

Verwendungszweck: Recombinant Human SELENOI/EPT1 Protein (GST Tag)

Sequenz: Met 1-Pro50

Produktmerkmale: Recombinant Human Ethanolaminephosphotransferase 1 is produced by our E.coli expression system and the target gene encoding Met1-Pro50 is expressed with a GST tag at the N-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: Ethanolaminephosphotransferase 1 (SELENOI)

Andere Bezeichnung: SELENOI/EPT1

Hintergrund:

Background: Ethanolaminephosphotransferase 1 (EPT1) is an enzyme that belongs to the CDP-Alcohol Phosphatidyltransferase Class-I Family. EPT1 is a Selenoprotein, which contains a Selenocysteine (Sec) residue at its active site. The Selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of Selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. EPT1 catalyzes Phosphatidylethanolamine biosynthesis from CDP-Ethanolamine. It plays a central role in the formation and maintenance of vesicular membranes. EPT1 is involved in the formation of Phosphatidylethanolamine via the 'Kennedy' pathway.

Synonym: Ethanolaminephosphotransferase 1, hEPT1, Selenoprotein I, SelI, EPT1, KIAA1724, SELI

Molekulargewicht: 32.3 kDa

UniProt: Q9C0D9