DEFB4A Protein (AA 24-64)

Produktnummer ABIN7319217

Recombinant DEFB4A-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für DEFB4A Protein (AA 24-64) (ABIN7319217)

Target: DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 24-64

Verwendungszweck: Recombinant Human β-Defensin 4A/DEFB4A Protein

Sequenz: Gly24-Pro64

Produktmerkmale: Recombinant Human beta-Defensin 4A is produced by our E.coli expression system and the target gene encoding Gly24-Pro64 is expressed.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))

Andere Bezeichnung: beta-Defensin 4A/DEFB4A

Hintergrund: BD-2,Beta 2,Beta-Defensin 2,Beta-Defensin 4A,DEFB102,DEFB2,DEFB4,DEFB4A,DEFB4B,Defensin,SAP1,Skin-Antimicrobial Peptide 1,hBD-2,β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38 % and 33 % amino acid sequence identity with mouse and rat BD3, respectively.

Molekulargewicht:

Calculated MW: 4.3 kDa

Observed MW: 9 kDa

Gen-ID: 100289462

UniProt: O15263