D Amino Acid Oxidase Protein (His tag)

Produktnummer ABIN7318393

Dieses Recombinant D Amino Acid Oxidase-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für D Amino Acid Oxidase Protein (His tag) (ABIN7318393)

Target: D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses D Amino Acid Oxidase Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human D-Amino-Acid Oxidase/DAO Protein (His Tag)

Sequenz: Met 1-Leu347

Produktmerkmale: Recombinant Human D-Amino-Acid Oxidase is produced by our E.coli expression system and the target gene encoding Met1-Leu347 is expressed with a 6His tag at the N-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 20 % Glycerol, 1 mM DTT, 2 mM EDTA, pH 8.0.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))

Andere Bezeichnung: D-Amino-Acid Oxidase/DAO

Hintergrund: D-Amino-Acid Oxidase,DAAO,DAMOX,DAO,D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. D-amino-acid oxidase regulates the level of the neuromodulator D-serine in the brain, has a high activity towards D-DOPA and contributes to dopamine synthesis. D-amino-acid oxidase could act as a detoxifying agent which removes D-amino acids accumulated during aging. It also acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups.

Molekulargewicht:

Calculated MW: 41.6 kDa

Observed MW: 40 kDa

Gen-ID: 1610

UniProt: P14920