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PPIB Protein (His tag)

Recombinant PPIB-Protein exprimiert in Human Cells.
Produktnummer ABIN7319504

Kurzübersicht für PPIB Protein (His tag) (ABIN7319504)

Target

Alle PPIB Proteine anzeigen
PPIB (Cyclophilin B (PPIB))

Protein-Typ

Recombinant

Spezies

  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Human

Quelle

  • 15
  • 4
  • 1
  • 1
Human Cells

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Aufreinigungstag / Konjugat

    Dieses PPIB Protein ist gelabelt mit His tag.

    Verwendungszweck

    Recombinant Human Cyclophilin B/PPIB Protein (His Tag)

    Sequenz

    Asp34-Ala212

    Produktmerkmale

    Recombinant Human Cyclophilin B is produced by our Mammalian expression system and the target gene encoding Asp34-Ala212 is expressed with a 6His tag at the C-terminus.

    Endotoxin-Niveau

    < 1.0 EU per μg as determined by the LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    PPIB (Cyclophilin B (PPIB))

    Andere Bezeichnung

    Cyclophilin B/PPIB

    Hintergrund

    Background: Cyclophilin B (SCYLP, CyPB and peptidyl-prolyl cis-trans isomerase B) is a 24 kDa glycoprotein member of the B subfamily of the cyclophilin-type PPIase family of molecules. It is both secreted and retained in the ER. When secreted, Cyclophilin B mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization, and facilitating the activity of additional chaperones.

    Synonym: CYP-S1, CYPB, HEL-S-39, OI9, SCYLP

    Molekulargewicht

    20.9 kDa

    UniProt

    P23284
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