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CMRF35-Like Molecule (CD300C2) protein (Fc Tag)

CD300C2 Spezies: Human Wirt: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318733
  • Target
    CMRF35-Like Molecule (CD300C2)
    Protein-Typ
    Recombinant
    Spezies
    Human
    Quelle
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Fc Tag
    Verwendungszweck
    Recombinant Human LMIR2/CD300C Protein (Fc Tag)
    Sequenz
    Gly21-Arg183
    Produktmerkmale
    Recombinant Human Leukocyte Mono Ig-like Receptor 2 is produced by our Mammalian expression system and the target gene encoding Gly21-Arg183 is expressed with a Fc tag at the C-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CMRF35-Like Molecule (CD300C2)
    Andere Bezeichnung
    LMIR2/CD300C
    Hintergrund

    Background: CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells, granulocytes, most myeloid cells, dendritic cells, and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.

    Synonym: CMRF35-Like Molecule 6, CLM-6, CD300 Antigen-Like Family Member C, CMRF35-A1, CMRF-35, Immunoglobulin Superfamily Member 16, IgSF16, CD300c, CD300C, CMRF35, CMRF35A, CMRF35A1, IGSF16

    Molekulargewicht
    44.9 kDa
    UniProt
    Q08708
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