Claudin 11 Protein (CLDN11) (Fc Tag)

Produktnummer ABIN7317330

Dieses Recombinant Claudin 11-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für Claudin 11 Protein (CLDN11) (Fc Tag) (ABIN7317330)

Target: Claudin 11 (CLDN11)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Claudin 11 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human CLDN11/Claudin-11 Protein (Fc Tag)

Sequenz: Val23-Arg82

Produktmerkmale: A DNA sequence encoding the human CLDN11 (O75508) (Val23-Arg82) was expressed with the Fc region of mouse IgG1 at the N-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Claudin 11 (CLDN11)

Andere Bezeichnung: CLDN11/Claudin-11

Hintergrund:

Background: Claudin-11, also known as CLDN11, belongs to the group of claudins. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands function as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.Claudin-11 is a tight junction associated protein and is a major component of central nervous system (CNS) myelin that is necessary for normal CNS function. Human blood-testis barrier disruption is related to a dysfunction of CLDN11 gene. It plays an important role in regulating proliferation and migration of oligodendrocytes.

Synonym: OSP,OTM

Molekulargewicht: 33.2 kDa

UniProt: O75508

Pathways: Hepatitis C