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CXCL2 Protein

Recombinant CXCL2-Protein exprimiert in Escherichia coli (E. coli).
Produktnummer ABIN7320503

Kurzübersicht für CXCL2 Protein (ABIN7320503)

Target

Alle CXCL2 Proteine anzeigen
CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Protein-Typ

Recombinant

Spezies

  • 15
  • 9
  • 6
  • 2
  • 1
  • 1
Maus

Quelle

  • 24
  • 2
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

> 95 % as determined by SDS-PAGE
  • Verwendungszweck

    Recombinant Mouse CXCL2/MIP-2 Protein

    Sequenz

    Ala28-Asn100

    Produktmerkmale

    Recombinant Mouse C-X-C motif chemokine 2 is produced by our E.coli expression system and the target gene encoding Ala28-Asn100 is expressed.

    Endotoxin-Niveau

    < 1.0 EU per μg as determined by the LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

    Andere Bezeichnung

    CXCL2/MIP-2

    Hintergrund

    Background: C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63 % aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.

    Synonym: MIP-2, chemokine ligand 2, C-X-C motif chemokine 2, GRO beta, GRO2, GROB, Gro-beta, Growth-regulated protein beta, Macrophage Inflammatory Protein-2-alpha, melanoma growth stimulatory activity beta, cxcl2, MGSA-b, MGSA-beta, MIP2A, MIP2-alpha, SCYB2.

    Molekulargewicht

    7.9 kDa

    UniProt

    P10889

    Pathways

    Cellular Response to Molecule of Bacterial Origin
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