CCL24 Protein (AA 27-119)

Produktnummer ABIN7320485

Dieses Recombinant CCL24-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für CCL24 Protein (AA 27-119) (ABIN7320485)

Target: CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 27-119

Verwendungszweck: Recombinant Mouse CCL24/Eotaxin-2 Protein

Sequenz: Val27-Val119

Produktmerkmale: Recombinant Mouse C-C Motif Chemokine 24 is produced by our E.coli expression system and the target gene encoding Val27-Val119 is expressed.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))

Andere Bezeichnung: CCL24/Eotaxin-2

Hintergrund: C-C motif chemokine 24,Ccl24,Eosinophil chemotactic protein 2,Eotaxin-2,Scya24,Small-inducible cytokine A24,Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares approximately 58 % amino acid sequence identity with human Ccl24. It is predominantly expressed in the jejunum and spleen and also be induced in the lung by allergen challengeand IL4. Mouse ccl24 has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Ccl24 is chemotactic for resting T-lymphocytes, eosinophils and can bind to CCR3. LPS and IL4 also differentially regulate the expression of Ccl24 in monocytes and macrophages.

Molekulargewicht:

Calculated MW: 10.3 kDa

Observed MW: 12 kDa

UniProt: Q9JKC0

Pathways: Regulation of Actin Filament Polymerization