CD96 Protein (CD96) (His tag)

Produktnummer ABIN7319442

Dieses Recombinant CD96-Protein wird in Human Cells exprimiert.

Kurzübersicht für CD96 Protein (CD96) (His tag) (ABIN7319442)

Target: CD96

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Human Cells

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD96 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human CD96 Protein (His Tag)(Active)

Sequenz: Val22-Met503

Produktmerkmale: Recombinant Human CD96 is produced by our Mammalian expression system and the target gene encoding Val22-Met503 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Human PVR-His(Cat: PKSH033563) at 10μg/ml(100 μl/well) can bind Biotinylated Human CD96-His. The ED50 of Human CD96-His is 27.54μg/mL.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CD96

Andere Bezeichnung: CD96

Hintergrund:

Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor (PVR), anectins and nectin-like protein family member serve to mediate cell-cell adhesion, cell migration, with the presence of an additional receptor, CD96. CD96 promotes NK cell adhesion to target cells expressing PVR, stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells.

Synonym: T-cell surface protein tactile, Cell surface antigen CD96, T cell-activated increased late expression protein, CD96

Molekulargewicht: 54.4 kDa