CD8B Protein (His tag)

Produktnummer ABIN7319333

Recombinant CD8B-Protein exprimiert in Human Cells.

Kurzübersicht für CD8B Protein (His tag) (ABIN7319333)

Target: CD8B (CD8b Molecule (CD8B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD8B Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human CD8 beta/CD8B Protein (His Tag)

Sequenz: Leu22-Pro170

Produktmerkmale: Recombinant Human T-Cell Surface Glycoprotein CD8 beta Chain is produced by our Mammalian expression system and the target gene encoding Leu22-Pro170 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CD8B (CD8b Molecule (CD8B))

Andere Bezeichnung: CD8 beta/CD8B

Hintergrund:

Background: T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

Synonym: T-Cell Surface Glycoprotein CD8 Beta Chain, CD8b, CD8B, CD8B1, LEU2, LY3, LYT3, P37

Molekulargewicht: 17.8 kDa

Pathways: T-Zell Rezeptor Signalweg