CD7 Protein (CD7) (His tag)

Produktnummer ABIN7318287

Dieses Recombinant CD7-Protein wird in Human Cells exprimiert.

Kurzübersicht für CD7 Protein (CD7) (His tag) (ABIN7318287)

Target: CD7

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD7 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human CD7/GP40 Protein (His Tag)

Sequenz: Ala26-Pro180

Produktmerkmale: Recombinant Human T-Cell Antigen CD7 is produced by our Mammalian expression system and the target gene encoding Ala26-Pro180 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CD7

Andere Bezeichnung: CD7/GP40

Hintergrund:

Background: T-Cell Antigen CD7 is a single-pass type I membrane protein that that belongs to the the immunoglobulin superfamily. Human CD7 is synthesized as a 240 amino acid precursor that contains a 25 amino acid signal sequence and a 215 amino acid mature chain with a Ig-like (immunoglobulin-like) domain. CD7 is normally expressed on all T-lymphocytes, NK-cells, pre-B lymphocytes and pleuripotent hematopoietic stem cells. CD7 plays an essential role in T-cell interactions, T-cell/B-cell interaction during early lymphoid development, T- and NK-cell activation and cytokine production. CD7 has been shown to interact with PIK3R1and SECTM1. However, the function of the CD7 protein in the immune system is still largely unknown.

Synonym: T-Cell Antigen CD7, GP40, T-Cell Leukemia Antigen, T-Cell Surface Antigen Leu-9, TP41, CD7

Molekulargewicht: 17.5 kDa

UniProt: P09564

Pathways: Cell-Cell Junction Organization