CD5L Protein (His tag)

Produktnummer ABIN7320432

Dieses Recombinant CD5L-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für CD5L Protein (His tag) (ABIN7320432)

Target: CD5L (CD5 Molecule-Like (CD5L))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 98 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD5L Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse CD5L Protein (His Tag)

Sequenz: Met 1-Val 352

Produktmerkmale: A DNA sequence encoding the extracellular domain (Met 1-Val 352) of mouse CD5L (NP_033820.2) precursor was expressed with a polyhistidine tag at the C-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: CD5L (CD5 Molecule-Like (CD5L))

Andere Bezeichnung: CD5L

Hintergrund: AAC-11,AI047839,Aim,Api6,Apoptosis inhibitor expressed by macrophages,Apoptosis inhibitory 6,CD5 antigen-like,CT-2,CT2,Cd5l,Pdp,SP-alpha,Sp-alpha,CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.

Molekulargewicht: 38 kDa

NCBI Accession: NP_033820

UniProt: Q9QWK4