CD38 Protein (AA 44-301) (Fc Tag)
Kurzübersicht für CD38 Protein (AA 44-301) (Fc Tag) (ABIN7320968)
Target
Alle CD38 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 44-301
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Aufreinigungstag / Konjugat
- Dieses CD38 Protein ist gelabelt mit Fc Tag.
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Verwendungszweck
- Recombinant Cynomolgus CD38/ADP-ribosyl Cyclase 1 Protein (Fc Tag)
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Sequenz
- Leu44-Ile301
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Produktmerkmale
- Recombinant Cynomolgus CD38 is produced by our Mammalian expression system and the target gene encoding Leu44-Ile301 is expressed with a Fc tag at the C-terminus.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Haltbarkeit
- 12 months
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- CD38
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Andere Bezeichnung
- CD38/ADP-ribosyl Cyclase 1
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Hintergrund
- ADP-ribosyl cyclase 1,CD38,T10,cyclic ADP-ribose hydrolase,CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
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Molekulargewicht
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Calculated MW: 57.0 kDa
Observed MW: 65-95 kDa
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UniProt
- Q5VAN0
Target
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