DCL1 Protein (Fc Tag)

Produktnummer ABIN7321088

Dieses Recombinant DCL1-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für DCL1 Protein (Fc Tag) (ABIN7321088)

Target: DCL1 (CD302) (CD302)

Protein-Typ: Recombinant

Spezies: Ratte

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by SDS-PAGE

Produktdetails

Aufreinigungstag / Konjugat: Dieses DCL1 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Rat CD302/CLEC13A Protein (Fc Tag)

Sequenz: Met1-His165

Produktmerkmale: A DNA sequence encoding the rat CD302 (Met1-His165) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: DCL1 (CD302) (CD302)

Andere Bezeichnung: CD302/CLEC13A

Hintergrund:

Background: CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 ectodomain contains only one CRD, whereas other type I transmembrane C-type lectins contain more than one domain (e.g. selectins and MMR). DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling. DCL-1 may be another cell/matrix adhesion receptor integrated in cell adhesion complexes and that DCL-1 dysfunction may affect APC adhesion and migration, causing suppression of APC function.

Synonym: CD302

Molekulargewicht: 43.7 kDa

NCBI Accession: NP_001013938

Pathways: Regulation of Actin Filament Polymerization