CD1d Protein (His tag)

Produktnummer ABIN7320378

Dieses Recombinant CD1d-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für CD1d Protein (His tag) (ABIN7320378)

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by SDS-PAGE

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD1d Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse CD1D/R3G1 Protein (His Tag)

Sequenz: Met 1-Gly 305

Produktmerkmale: A DNA sequence encoding the extracellular domain of mouse CD1D (NP_031665.2) (Met 1-Gly 305) was fused with a polyhistidine tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Andere Bezeichnung: CD1D/R3G1

Hintergrund:

Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 1 (CD1) is a member of CD system. It's a family of glycoproteins expressed on the surface of various human antigen- presenting cells which are implicated in the presentation of lipid antigens to T-cells. Due to the different lipid anchoring, the CD1 family is classified into two groups: group1 (CD1a-c) and group2 (CD1d). CD1d with lipid antigens activate NK T-cells which rapidly produce Th1 and Th2 cytokines after been activated.

Synonym: AI747460,CD1.1,Cd1a,Cd1d,Ly-38

Molekulargewicht: 33.7 kDa

NCBI Accession: NP_031665

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process