CD160 Protein (CD160) (His tag)

Produktnummer ABIN7320849

Dieses Recombinant CD160-Protein wird in Human Cells exprimiert.

Kurzübersicht für CD160 Protein (CD160) (His tag) (ABIN7320849)

Target: CD160

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD160 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse CD160/BY55 Protein (His Tag)

Sequenz: Gly28-Ser160

Produktmerkmale: Recombinant Mouse CD160 is produced by our Mammalian expression system and the target gene encoding Gly28-Ser160 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CD160

Andere Bezeichnung: CD160/BY55

Hintergrund:

Background: CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and smal lintestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.

Synonym: CD160 Antigen, Natural Killer Cell Receptor BY55, CD160, BY55

Molekulargewicht: 15.8 kDa

UniProt: Q8VC80