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CARTPT Protein

Dieses Recombinant CARTPT-Protein wird in HEK-293 Cells produziert.
Produktnummer ABIN7317276

Kurzübersicht für CARTPT Protein (ABIN7317276)

Target

Alle CARTPT Proteine anzeigen
CARTPT (CART Prepropeptide (CARTPT))

Protein-Typ

Recombinant

Spezies

  • 3
  • 3
  • 2
  • 1
Human

Quelle

  • 4
  • 2
  • 2
  • 1
HEK-293 Cells

Reinheit

> 90 % as determined by reducing SDS-PAGE.
  • Verwendungszweck

    Recombinant Human CART/CARTPT Protein

    Sequenz

    Met 1-Leu116

    Produktmerkmale

    A DNA sequence encoding the human CARTPT (NP_004282.1) (Met1-Leu116) was expressed with five amino acids (DDDDK) at the C-terminus.

    Endotoxin-Niveau

    < 1.0 EU per μg of the protein as determined by the LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile PBS, pH 7.4

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CARTPT (CART Prepropeptide (CARTPT))

    Andere Bezeichnung

    CART/CARTPT

    Hintergrund

    Background: Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions as key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate, a precurcor for several classes of essential metabolites. FDPS catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Functions of FDPS may be inactivated by interferon-induced RSAD2. This inactivation may result of disruption of lipid rafts at the plasma membrane, and thus have an antiviral effect since many enveloped viruses need lipid rafts to bud efficiently out of the cell.

    Synonym: CART

    Molekulargewicht

    10.6 kDa

    NCBI Accession

    NP_004282

    Pathways

    Hormone Transport, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Feeding Behaviour
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