Calcitonin Protein (Calca) (His tag)

Produktnummer ABIN7318222

Recombinant Calcitonin-Protein exprimiert in Human Cells.

Kurzübersicht für Calcitonin Protein (Calca) (His tag) (ABIN7318222)

Target: Calcitonin (Calca)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Calcitonin Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Calcitonin/CALCA Protein (His Tag)

Sequenz: Ala26-Asn141

Produktmerkmale: Recombinant Human Calcitonin is produced by our Mammalian expression system and the target gene encoding Ala26-Asn141 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Calcitonin (Calca)

Andere Bezeichnung: Calcitonin/CALCA

Hintergrund:

Background: Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). Its importance in humans has not been as well established as its importance in other animals, as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

Synonym: Calcitonin, Katacalcin, Calcitonin Carboxyl-Terminal Peptide, CCP, PDN-21, CALCA, CALC1

Molekulargewicht: 13.8 kDa

UniProt: P01258