Cadherin 13 Protein (CDH13)

Produktnummer ABIN7321153

Recombinant Cadherin 13-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für Cadherin 13 Protein (CDH13) (ABIN7321153)

Target: Cadherin 13 (CDH13)

Protein-Typ: Recombinant

Spezies: Ratte

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by SDS-PAGE

Produktdetails

Verwendungszweck: Recombinant Rat Cadherin-13/CDH13 Protein

Sequenz: Met1-Ala692

Produktmerkmale: A DNA sequence encoding the rat CDH13 (NP_620244.1)(Met1-Ala692) was expressed with six amino acids (LEVLFQ) at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Cadherin 13 (CDH13)

Andere Bezeichnung: Cadherin-13/CDH13

Hintergrund:

Background: CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer.

Synonym: CDH13

Molekulargewicht: 74.3 kDa

NCBI Accession: NP_620244

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization