Cadherin 13 Protein (CDH13) (AA 1-692)

Produktnummer ABIN7321153

Recombinant Cadherin 13-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für Cadherin 13 Protein (CDH13) (AA 1-692) (ABIN7321153)

Target: Cadherin 13 (CDH13)

Protein-Typ: Recombinant

Spezies: Ratte

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 1-692

Verwendungszweck: Recombinant Rat Cadherin-13/CDH13 Protein

Sequenz: Met1-Ala692

Produktmerkmale: A DNA sequence encoding the rat CDH13 (NP_620244.1)(Met1-Ala692) was expressed with six amino acids (LEVLFQ) at the C-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Cadherin 13 (CDH13)

Andere Bezeichnung: Cadherin-13/CDH13

Hintergrund: CDH13,CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer.

Molekulargewicht:

Calculated MW: 74.3 kDa

Observed MW: 84-96 kDa

NCBI Accession: NP_620244

UniProt: A0A096MK38

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization