CRP Protein

Produktnummer ABIN7194465

Dieses Recombinant CRP-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für CRP Protein (ABIN7194465)

Target: CRP (C-Reactive Protein (CRP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Verwendungszweck: Recombinant Human CRP/C-Reactive Protein

Sequenz: Met 1-Pro224

Produktmerkmale: A DNA sequence encoding the human CRP (P02741-1) (Met1-Pro224) was expressed and purified.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 0.2M NaCl, 5 mM CaCl2, pH 8.0

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CRP (C-Reactive Protein (CRP))

Andere Bezeichnung: CRP/C-Reactive

Hintergrund:

Background: C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monitor many human diseases. However, CRP is likely to have important host defence, scavenging and metabolic functions through its capacity for calcium-dependent binding to exogenous and autologous molecules containing phosphocholine (PC) and then activating the classical complement pathway. CRP may also have pathogenic effects and the recent discovery of a prognostic association between increased CRP production and coronary atherothrombotic events is of particular interest.

Synonym: C-Reactive Protein, CRP, PTX1

Molekulargewicht: 23 kDa

Pathways: Carbohydrate Homeostasis