Biglycan Protein (BGN) (Fc Tag)

Produktnummer ABIN7320153

Dieses Recombinant Biglycan-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für Biglycan Protein (BGN) (Fc Tag) (ABIN7320153)

Target: Biglycan (BGN)

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 85 % as determined by SDS-PAGE

Produktdetails

Aufreinigungstag / Konjugat: Dieses Biglycan Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Mouse Biglycan/BGN Protein (Fc Tag)

Sequenz: Met1-Lys369

Produktmerkmale: A DNA sequence encoding the mouse BGN (Met1-Lys369) was expressed with the Fc region of human IgG1 at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Biglycan (BGN)

Andere Bezeichnung: Biglycan/BGN

Hintergrund:

Background: Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.

Synonym: BG,DSPG1,PG-S1,PGI,SLRR1A

Molekulargewicht: 66.5 kDa

NCBI Accession: NP_031568

Pathways: Glycosaminoglycan Metabolic Process