ANG Protein (AA 25-147)

Produktnummer ABIN7318153

Dieses Recombinant ANG-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für ANG Protein (AA 25-147) (ABIN7318153)

Target: ANG (Angiogenin (ANG))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 25-147

Verwendungszweck: Recombinant Human Angiogenin/ANG Protein

Sequenz: Gln25-Pro147

Produktmerkmale: Recombinant Human Angiogenin is produced by our E.coli expression system and the target gene encoding Gln25-Pro147 is expressed.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: ANG (Angiogenin (ANG))

Andere Bezeichnung: Angiogenin/ANG

Hintergrund: ANG,Angiogenin,RNASE5,RNase 5,Ribonuclease 5,Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Angiogenin is a potent stimulator of new blood vessel formation. And Angiogenin is endocytosed and translocated to the nucleus by binding to actin on the surface of endothelial cells. Angiogenic activity is regulated by interaction with RNH1 in vivo. In addition, Angiogenin is associated with susceptibility to amyotrophic lateral sclerosis, which is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord.

Molekulargewicht:

Calculated MW: 14.3 kDa

Observed MW: 14 kDa

Gen-ID: 283

UniProt: P03950