AKR1C2 Protein

Produktnummer ABIN7318143

Dieses Recombinant AKR1C2-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für AKR1C2 Protein (ABIN7318143)

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Verwendungszweck: Recombinant Human AKR1C2 Protein

Sequenz: Met 1-Tyr323

Produktmerkmale: Recombinant Human Aldo-Keto Reductase Family 1 Member C2 is produced by our E.coli expression system and the target gene encoding Met1-Tyr323 is expressed.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, pH 8.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Andere Bezeichnung: AKR1C2

Hintergrund:

Background: Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).

Synonym: Aldo-Keto Reductase Family 1 Member C2, 3-Alpha-HSD3, Chlordecone Reductase Homolog HAKRD, Dihydrodiol Dehydrogenase 2, DD-2, DD2, Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, DD/BABP, Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase, Type III 3-Alpha-Hydroxysteroid Dehydrogenase, AKR1C2, DDH2

Molekulargewicht: 36.7 kDa

UniProt: P52895

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process