MUC17 Protein (AA 4131-4390) (His tag)

Produktnummer ABIN7013506

Recombinant MUC17-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für MUC17 Protein (AA 4131-4390) (His tag) (ABIN7013506)

Target: MUC17 (Mucin 17, Cell Surface Associated (MUC17))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: >90 % as determined by SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 4131-4390

Aufreinigungstag / Konjugat: Dieses MUC17 Protein ist gelabelt mit His tag.

Produktmerkmale: Human MUC-17 Protein, His Tag

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Antigendetails

Target: MUC17 (Mucin 17, Cell Surface Associated (MUC17))

Andere Bezeichnung: MUC-17

Hintergrund: Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

Molekulargewicht: 31.2 kDa