Claudin 3 Protein (CLDN3) (AA 30-80) (Fc Tag)

Produktnummer ABIN6964182

Dieses Recombinant Claudin 3-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für Claudin 3 Protein (CLDN3) (AA 30-80) (Fc Tag) (ABIN6964182)

Target: Claudin 3 (CLDN3)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Produktdetails

Proteineigenschaft: AA 30-80

Aufreinigungstag / Konjugat: Dieses Claudin 3 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant human CLDN3 protein with C-terminal human Fc tag

Spezifität: CLDN3 (Arg30-Arg80) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: Claudin 3 (CLDN3)

Andere Bezeichnung: CLDN3

Hintergrund: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]

Molekulargewicht: predicted molecular mass of 31.8 kDa after removal of the signal peptide. The apparent molecular mass of CLDN3-hFc is 35-40 kDa due to glycosylation.

UniProt: O15551

Pathways: Hepatitis C