CD4 Protein (CD4) (Fc Tag)

Produktnummer ABIN6964180

Dieses Recombinant CD4-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für CD4 Protein (CD4) (Fc Tag) (ABIN6964180)

Target: CD4

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD4 Protein ist gelabelt mit Fc Tag.

Sequenz: CD4(Lys26-Trp390)+hFc(Glu99-Ala330)

Produktmerkmale: Tagged Protein: C-Human Fc tag

Aufreinigung: affinity purification

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Konservierungsmittel: Without preservative

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C for 12 months (Avoid repeated freezing and thawing)

Haltbarkeit: 12 months

Antigendetails

Target: CD4

Andere Bezeichnung: CD4

Hintergrund: Synonymes: CD4,CD4mut,LEU3
Description: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Molekulargewicht: 65.67 kDa

UniProt: P01730

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events