SARS-CoV-2 NSP7, NSP8 protein (His tag)
Kurzübersicht für SARS-CoV-2 NSP7, NSP8 protein (His tag) (ABIN6952711)
Target
Protein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- His tag
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Verwendungszweck
- SARS-CoV-2 (COVID-19) NSP7&NSP8 Protein, His Tag
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Sequenz
- AA 1-83
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Produktmerkmale
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SARS-CoV-2 NSP7&NSP8, His Tag (NS8-C5125) is expressed from E.coli cells. It contains AA Ser 1 - Gln 83 (NSP7) & Ala 1 - Gln 198 (NSP8) (Accession # YP_009725303.1 (NSP7) & YP_009725304.1 (NSP8). Predicted N-terminus: Met
This protein carries a polyhistidine tag. -
Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4
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Lagerung
- -80 °C
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Informationen zur Lagerung
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The product MUST be stored at -70°C or lower upon receipt
-70°C for 3 months under sterile conditions.
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- SARS-CoV-2 NSP7, NSP8
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Andere Bezeichnung
- SARS-CoV-2 NSP7 & NSP8
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Substanzklasse
- Viral Protein
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Hintergrund
- During the formation of the coronaviral replication/transcription complex, essential steps include processing of the conserved polyprotein nsp7-10 region by the main protease Mpro and subsequent complex formation of the released nsp's. Upon infecting host cells, coronaviruses assemble a multi-subunit RNA-synthesis complex of viral non-structural proteins (nsp) responsible for the replication and transcription of the viral genome. non-structural proteins 7 (NSP7) forms a hexadecamer with nsp8 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.
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Molekulargewicht
- 32.1 kDa
Target
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