CCL5 Protein (AA 24-91)
Kurzübersicht für CCL5 Protein (AA 24-91) (ABIN6952206)
Target
Alle CCL5 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 24-91
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Sequenz
- SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
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Produktmerkmale
- Recombinant Human CCL5 (Rantes)
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Endotoxin-Niveau
- <0.01 EU per 1μg of the protein by the LAL method
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Biological Activity Comment
- EC50 = 0.13 nM determined by Migration Assay in cells expressing recombinant CCR5
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Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) protein (Fc Tag)
CCL5 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) protein (His tag,SUMO Tag)CCL5 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) protein (His-Avi Tag,Biotin)CCL5 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) (Active) protein (Biotin)CCL5 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 5 (CCL5) protein (His tag)CCL5 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) (Active) protein (His tag)CCL5 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 1-91) protein (GST tag)CCL5 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) protein (Fc Tag)CCL5 Spezies: Human Wirt: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. -
Haltbarkeit
- 12 months
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- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
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Andere Bezeichnung
- CCL5 (Rantes)
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Hintergrund
- Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) (CCL5) is a proinflammatory chemokine that induces migration and activation of leukocytes, as well as implication in HIV infection. It binds to cell surface receptors CCR1, CCR3, CCR4, and CCR5. Its biological effects on leukocyte activation and HIV infection displays dependence on concentration and on the binding of cell surface glycosaminoglycans.
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Molekulargewicht
- 7.851 kDa
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UniProt
- P13501
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
Target
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