NXT1 Protein (AA 1-140) (His tag)

Produktnummer ABIN667905

Dieses Recombinant NXT1-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für NXT1 Protein (AA 1-140) (His tag) (ABIN667905)

Target: NXT1 (NTF2-Related Export Protein 1 (NXT1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 85% by SDS-PAGE

Produktdetails

Proteineigenschaft: AA 1-140

Aufreinigungstag / Konjugat: Dieses NXT1 Protein ist gelabelt mit His tag.

Sequenz: MASVDFKTYV DQACRAAEEF VNVYYTTMDK RRRLLSRLYM GTATLVWNGN AVSGQESLSE FFEMLPSSEF QISVVDCQPV HDEATPSQTT VLVVICGSVK FEGNKQRDFN QNFILTAQAS PSNTVWKIAS DCFRFQDWAS

Produktmerkmale: NXT1, 1-140aa, Human, His tag, E.coli

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: NXT1 (NTF2-Related Export Protein 1 (NXT1))

Andere Bezeichnung: NXT1

Hintergrund: NXT1 functions as a nuclear export factor in both RAN (Ras-related nuclear protein) and CRM1 (required for chromosome region maintenance) dependent pathways. It is found to stimulate the export of u1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. This protien heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. Recombinant human NXT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Molekulargewicht: 18 kDa (160aa) confirmed by MALDI-TOF

NCBI Accession: NP_037380