Nanog Protein (AA 1-305)

Produktnummer ABIN667504

Nanog-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für Nanog Protein (AA 1-305) (ABIN667504)

Target: Nanog (NANOG) (Nanog Homeobox (NANOG))

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 % by SDS - PAGE

Produktdetails

Proteineigenschaft: AA 1-305

Produktmerkmale: NANOG, 1-305aa, Human, E.coli

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 5% glycerol

Lagerung: 4 °C

Antigendetails

Target: Nanog (NANOG) (Nanog Homeobox (NANOG))

Andere Bezeichnung: NANOG

Hintergrund: Nanog homeobox, also known as nanog, is a member of the homeobox family of DNA binding transcription factors that has been shown to maintain pluripotency of embryonic stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. Synonyms: Nanog homeobox, Homeobox transcription factor Nanog, homeobox transcription factor Nanog-delta 48. NCBI no.: NP_079141

Molekulargewicht: 34.6 kDa (305aa)

Pathways: Stem Cell Maintenance