FKBP2 Protein (AA 22-142)

Produktnummer ABIN667129

Recombinant FKBP2-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für FKBP2 Protein (AA 22-142) (ABIN667129)

Target: FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS), Enzyme Activity Assay (EAA)

Reinheit: > 90% by SDS-PAGE

Produktdetails

Proteineigenschaft: AA 22-142

Sequenz: MATGAEGKRK LQIGVKKRVD HCPIKSRKGD VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL

Produktmerkmale: FKBP2, 22-142aa, Human, E.coli

Endotoxin-Niveau: < 1 EU per 1ug of protein (determined by LAL method)

Biological Activity Comment: Specific activity is > 700nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmol of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. In 20mM Tris buffer(pH 8.0) containing 10% glycerol, 1mM DTT.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))

Andere Bezeichnung: FKBP13/FKBP2

Hintergrund: FKBP2 is peptidyl proline isomerase enzyme and a member of the immunophilin protein family. This protein is predominantly expressed in thymus and T cells and plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Recombinant FKBP2 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Molekulargewicht: 13.4 kDa (122aa) confirmed by MALDI-TOF

NCBI Accession: NP_001128680