Retinoid X Receptor gamma Protein (AA 111-228)

Produktnummer ABIN666801

Dieses Recombinant Retinoid X Receptor gamma-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für Retinoid X Receptor gamma Protein (AA 111-228) (ABIN666801)

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 95 % by SDS - PAGE

Produktdetails

Proteineigenschaft: AA 111-228

Produktmerkmale: RXR-alpha( Retinoid x receptor, 111-228aa, Human) Recombinant, expressed in E.coli)

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl pH7.5, 0.1M NaCl, 5mM beta-Mercaptoethanol

Lagerung: 4 °C

Antigendetails

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Andere Bezeichnung: RXR-alpha (Retinoid X Receptor)

Hintergrund: The retinoid X receptor(RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors(RAR), thyroid hormone receptors(TR), vitamin D receptors and peroxisome proliferators-activated receptors(PPAR). The RXR family includes three difference isoforms, RXR alpha, beta, gamma. Human RXR alpha gene is localized on 9q34.9 and encodes two major isoforms(RXR alpha1, RXR alpha2). The DNA binding domain of RXR(111-228aa) was over expressed in E.coli and purified by using conventional column chromatography techniques. Synonyms: RXRA, NR2B1, RXR-alpha, Retinoid x receptor, Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1, Retinoic acid receptor RXR-alpha, FLJ16020, FLJ16733, MGC102720, Retinoic acid receptor RXR alpha, RXR alpha1, RXRalpha1, RXRA1. NCBI no.: NP_002948

Molekulargewicht: 13.6 kDa (119 aa), confirmed by MALDI-TOF.

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway