COMT Protein (AA 51-271)

Produktnummer ABIN666744

Dieses Recombinant COMT-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für COMT Protein (AA 51-271) (ABIN666744)

Target: COMT (Catechol-O-Methyltransferase (COMT))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 95 % by SDS - PAGE

Produktdetails

Proteineigenschaft: AA 51-271

Produktmerkmale: COMT, 51-271 aa, Human, Recombinant, E.coli

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM MgCl2, 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: COMT (Catechol-O-Methyltransferase (COMT))

Andere Bezeichnung: COMT

Hintergrund: Catechol-O-methyltrasferase (COMT) is an enzyme that catalyses the transfer of the methyl group of S-adenosylmethionine (SAM) into catechol substrates such as levodopa, dopamine, epinephrine, and norepinephirine in the presence of Mg2+. COMT appears to be located in the postsynaptic neuron and plays roles in the metabolism of catechol estrogens and the inactivation of catecholamine neurotransmitters though enzymatic degradation. COMT inhibitors prevent levodopa degradation, increase its availability and are used in the treatment of patients with Parkinson's disease. Recombinant human COMT protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Catechol-O-methyltransferase , Catechol-O-methyltransferase , COMT. NCBI no.: NP_000745

Molekulargewicht: 24.4 kDa (221 aa), confirmed by MALDI-TOF.

Pathways: Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interaktom