BMP4 Protein (AA 293-408)

Produktnummer ABIN666737

Dieses Recombinant BMP4-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für BMP4 Protein (AA 293-408) (ABIN666737)

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 95 % by SDS - PAGE

Produktdetails

Proteineigenschaft: AA 293-408

Produktmerkmale: BMP- 4, 293-408aa, Human, Recombinant, E.coli

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 10mM Sodium citrate buffer (pH 3.5), 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Andere Bezeichnung: BMP- 4

Hintergrund: Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic protein family which belongs to the TGF-beta superfamily. This protein is a vital regulatory molecule that functions throughout bone and cartilage development, specifically tooth development, limb formation, bone induction, and fracture repair. In human embryonic development, BMP- 4 is required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. And it is overexpressed in patients with fibrodysplasia ossificans progressiva. Recombinant BMP-4 was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: BMP-2B, DVR4, Bone morphogenetic protein 4 BMP 4, BMP2B, BMP2B1, ZYME, BMP4. NCBI no.: NP_001193

Molekulargewicht: 13.2 kDa (117 aa), confirmed by MALDI-TOF.

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development